ARI Orthopaedics Conference
ARI Orthopaedics, Science with Open Discussion

2023 eCM21: Bone and Fracture Repair
10th – 12th July 2023, Congress Center, Davos, Switzerland

Keynote program (subject to change)

Monday, July 10th


08:30 – 08:45    Esther Wehrle (CH) AO Research Institute

08:45 – 09:00    Sophie Verrier (CH) Welcome to Davos

Session 1          Opening Session: New clinical developments

09:00 – 09:30    Hamish Simpson (UK)The non-union timeline: when is the fate of a fracture decided?

09:30 – 10:00    Peter Giannoudis (UK) Stem cells for bone repair, a clinical perspective

Session 2          Mechanobiology

10:30 – 11:00    David Hoey (IE)
Targeting mechanosignalling to modulate bone repair

11:00 – 11:30    Andrew Pitsillides
Bone Mechanoadaptation – local to whole-organ considerations’

Session 3         ISFR Joint Session

15:00 – 15:30    Vaida Glatt (US)
Biomimetic Hematoma to Enhance Bone Healing: Current Status and Future Clinical Implications

15:30 – 16:00    Louis WH Cheung (HK)
External biomechanical stimulation as an approach to stimulate fracture healing

16:00 – 16:30    Enrique Gómez Barrena (ES)
Clinical trials on expanded MSCs for bone regeneration

Session 4          Innervation and angiogenesis

16:30 – 17:00   Shukry James Habib (CH)
A novel bandage for bone repair

17:00 – 17:30   Andrea Banfi (CA)
The interplay of angiogenesis and osteogenesis for bone regeneration

Tuesday, July 11th

Session 5          Omics and Biomarkers

08:30 – 09:00    Kurt Hankenson (US)
Utilizing single cell RNA sequencing to study poor fracture healing

09:00 – 09:30    Esther Wehrle (DE)
Individualized omics-based preclinical models for bone healing

Session 6          Cell and Gene Delivery

11:00 – 11:30    Elizabeth R. Balmayor (NL)
cmRNA and its delivery for Bone regeneration

11:30 – 12:00    Yu-Chen (Andy) Hu (TW)
Intelligent CRISPR design for Bone regeneration

Group Photo, Free afternoon & eCM walk Lunch (Lunch not provided)

18:00 Dinner at Walserhuus Sertig

Wednesday, July 12th

Session 7          Fracture repair- more than just bone

08:30 – 09:00    Anita Ignatius (D)
Mast cells - Crucial modulators in osteoporotic fracture healing

09:00 – 09:30    Rik Osinga (CH)
Role of soft tissue in fracture-related infection (FRI) and periprosthetic joint infection (PJI)

Session 8          Implants and Materials   

11:00 – 11:30    Julian Antoniac (RO)
Biodegradable magnesium alloys for trauma implants

11:30 – 12:00    Markus Windolf (CH)
From a theory to a product, the biphasic plate


Session 9          Preclinical models and ex vivo alternatives      

14:30 – 15:00     Anja Hauser (D)
Longitudinal intravital imaging of bone marrow, immune dynamics and fracture repair

15:00 – 15:30    Matteo Moretti (CH)
Engineering 3D Human Multicellular Bone in vitro Models as Anti-tumor Drug Screening Systems

         Awards and conference closing      

15:45 – 16:15    Brett D. Crist (US)
Berton Rahn Research Award winner 2023
RIA versus BMC as orthobiologic augments to allografts

16:15 – 16:45    Martin Stoddart (CH)
Awards and conference closing


We advise all presenters to look at the TIPS FOR TALKS (290kB) presentation and read these guidelines (34kB) before starting to prepare their talks. Science is in the detail. It is the lifeblood of science to discuss.
All invited talks are 20 minutes (20-30 slides) to allow 10 minutes discussion per talk.
All submitted talks are 10 minutes (10-15 slides) to allow 5 minutes discussion per talk.
Chairpersons will cut people off who try to use this time for their talks!
Please bring a copy of your talk on CD or USB stick to give to Presentation Support, Sunday morning at Registration.

Paper Submission
We invite all participants to submit a paper (either original research report or original review) to the European Cells & Materials (eCM) online 'Open & Free Access' journal..